Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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166
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166
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-alkylC8-amine
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry
167
Tocris Bioscience™ Janelia Fluor 549, SE
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Yellow dye (Reactive group: NHS ester). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, flow and live cell imaging
168
Tocris Bioscience™ RNA Imaging Probe 1c
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Fluorogenic RNA imaging probe
169
Tocris Bioscience™ TRPC6-PAM-C20
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Selective TRPC6 positive allosteric modulator
| CAS | 667427-75-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 3-(3-,4-Dihydro-6,7-dimethoxy-3,3-dimethyl-1-isoquinolinyl)-2H-1-benzopyran-2-one |
| Molecular Formula | C22H21NO4 |
170
Tocris Bioscience™ CRT 0105950
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Potent LIMK1/2 inhibitor
171
Tocris Bioscience™ LL-K9-3
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective HyT-based degrader of the CDK9-cyclin T1 complex
172
R&D Systems™ Cy5-Fuc Labeled M1N1f
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Can be used as a ligand for lectins and to study glycan protein interaction, substrate for various glycosidases and glycosyltransferases and a scaffold for the synthesis of various glycan epitopes such as sialyl Lewis X structures.
173
Tocris Bioscience™ Nicotinamide Riboside
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NAD+ precursor; substrate for nicotinamide riboside kinases
174
Tocris Bioscience™ iP300v
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Small and Specialty Supplier Partner
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Negative control for iP300w (Cat. No. 7270)
175
Tocris Bioscience™ AZ 12799734
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Potent TGF-βRI inhibitor
| CAS | 1117684-36-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[[4-[(2.6-Dimethyl-3-pyridinyl)oxy]-2-pyridinyl]amino]benzenesulfonamide |
| Molecular Formula | C18H18N4O3S |
176
Manumycin A, MP Biomedicals™
CAS: 52665-74-4 Molecular Formula: C31H38N2O7 Synonym: Manumycin A, manumycin, Ucfi-C, AC1O5PHE, UNII-OIQ298X4XD
| CAS | 52665-74-4 |
|---|---|
| Synonym | Manumycin A, manumycin, Ucfi-C, AC1O5PHE, UNII-OIQ298X4XD |
| Molecular Formula | C31H38N2O7 |
177
Tocris Bioscience™ Ambrisentan
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Selective ETA antagonist
178
Tocris Bioscience™ Pomalidomide 4'-alkylC2-azide
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
179
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Pleconaril, Thermo Scientific™
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Pleconaril, Thermo Scientific™
CAS: 153168-05-9 Molecular Formula: C18 H18 F3 N3 O3 Molecular Weight (g/mol): 381.36 MDL Number: MFCD00923611 InChI Key: KQOXLKOJHVFTRN-UHFFFAOYSA-N IUPAC Name: 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole SMILES: CC1=NOC(CCCOC2=C(C)C=C(C=C2C)C2=NOC(=N2)C(F)(F)F)=C1
| CAS | 153168-05-9 |
|---|---|
| Molecular Weight (g/mol) | 381.36 |
| MDL Number | MFCD00923611 |
| SMILES | CC1=NOC(CCCOC2=C(C)C=C(C=C2C)C2=NOC(=N2)C(F)(F)F)=C1 |
| IUPAC Name | 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole |
| InChI Key | KQOXLKOJHVFTRN-UHFFFAOYSA-N |
| Molecular Formula | C18 H18 F3 N3 O3 |
180
Tocris Bioscience™ TL 13-22
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for TL 13-12