Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Molecular Weight (g/mol)
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Color
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Quantity
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166
Tocris Bioscience™ Conivaptan Hydrochloride
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Very high affinity vasopressin V1A and V2 antagonist; orally bioavailable
| CAS | 168626-94-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][benzazepin-6(1H)-yl)carbonyl]phenyl-[1,1'-biphenyl]-2-carboxamide hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C32H26N4O2.HCl |
| Formula Weight | 535.04 |
167
Tocris Bioscience™ Auxin
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Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone
168
Tocris Bioscience™ MMG 11
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TLR2 antagonist
| Target | Toll-like Receptor Antagonists |
|---|---|
| CAS | 313254-94-3 |
| Purity | 97% |
| Chemical Name or Material | Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H14O7 |
169
Tocris Bioscience™ GSK 2795039
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NADPH oxidase 2 (NOX2) inhibitor
| Target | NADPH Oxidase Inhibitors |
|---|---|
| CAS | 1415925-18-6 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H26N6O2S |
170
Tocris Bioscience™ SB 290157 trifluoroacetate
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Potent C3a receptor antagonist
171
Tocris Bioscience™ VH 032 amide-alkylC10-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VH 032-alkylC10-amine
172
Tocris Bioscience™ PND 1186
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Potent FAK inhibitor; orally bioavailable
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H26F3N5O3 |
| Formula Weight | 501.51 |
173
Tocris Bioscience™ VH 032 phenol-alkylC6-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VH 032 phenol-alkylC6-amine
174
Tocris Bioscience™ CGI 1746
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent, reversible BTK inhibitor
| Target | Brutons Tyrosine Kinase (BTK) Inhibitors |
|---|---|
| CAS | 910232-84-7 |
| Purity | 0.97 |
| Chemical Name or Material | N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C34H37N5O4 |
175
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-PEG1-amine
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Thalidomide-PEG1-ethylamine
176
Tocris Bioscience™ cis VH 032, amine dihydrochloride
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Negative control for VH 032, amine
177
Tocris Bioscience™ CIMBA hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective G protein-coupled estrogen receptor (GPER) antagonist
178
Tocris Bioscience™ Tricyclic cytosine tC
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent tricyclic cytosine analog for RNA imaging
179
Tocris Bioscience™ GSK 215
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Potent and selective focal adhesion kinase (FAK) degrader
180
Tocris Bioscience™ N-Acetylcysteine
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Glutathione (GSH) precursor; maintains stem cell function in culture.